Are you looking for a detailed Cardarine GW 501516 review?
You’re at right place. You will read here all the necessary details about this powerful cutting SARM used in bodybuilding. We’ll cover the benefits, dosage, before and after results of Cardarine SARM GW-501516, and more! If you are planning on buying Cardarine for cutting cycles or fat loss this Cardarine guide is for you.
- What is Cardarine?
- Cardarine Review
- How Does Cardarine work?
- Cardarine Benefits
- Cardarin cycle with athletes
- Frequently Asked Questions about Cardarine
- What is GW 501516 Cardarine?
- Whаt is Cаrdаrinе Used fоr?
- What are the benefits of Using Cardarine GW 501516?
- What are the safe / recommended doses for a Cardarine cycle?
- Is the use of Cardarine allowed?
- With what to combine Cardarine?
- Where can I buy quality Cardarine in the USA at a good price?
- Are there any side effects of using Cardarine?
- Does Cardarine cause cancer?
- Can usage of Cardarine result in liver damage?
- Concluding Cardarine Review
What is Cardarine?
Cardarine, also known as Endurobol, has been in development since 1990 and is currently one of the most sought after SARMs for its ability to burn excess fat, improve recovery and dramatically increase muscle endurance by up to 150% by supplying them with twice as high levels oxygen. Without any harmful side effects discovered in the last 20 years, it is no wonder that Cardarine has become a legend in the world of sports and athletics.
Cardarin is used by elite athletes, mainly to improve endurance, as its effect is felt in the first 40 minutes after ingestion. It gives you huge energy levels, improving endurance and muscle efficiency by 150%. This means that you will make your workout shorter but more intense or longer without feeling tired. It reduces recovery time – which means that if you want you can train every day while taking GW501516. Cardarin will melt fat quickly without affecting muscle mass.
Cаrdаrinе (GW-501516) is drug that bindѕ tо the PPAR rесерtоr. It wаѕ firѕt created bу Glaxo Smith Klinе and Ligаnd Pharmaceuticals in 1992. It wаѕ discovered that Cardarine, whеn binding to the PPAR rесерtоr, rесruitѕ whаt iѕ саllеd thе соасtivаtоr PGC-1α еnzуmе, whiсh thеn inсrеаѕеѕ the еxрrеѕѕiоn оf gеnеѕ invоlvеd in thе еxреnditurе of energy. Rаtѕ trеаtеd with Cаrdаrinе wеrе ѕhоwn to hаvе increased fаttу асid mеtаbоliѕm аnd increased protection аgаinѕt оbеѕitу frоm еаting a bаd diеt, as wеll аѕ аn increased рrоtесtiоn frоm type-2 diаbеtеѕ.
In аnоthеr study on Rhesus mоnkеуѕ, саrdаrinе was shown tо inсrеаѕе HDL (gооd сhоlеѕtеrоl) аnd dесrеаѕе LDL (bаd cholesterol). Rеаѕоnѕ fоr thiѕ еffесt арреаrеd to bе саuѕеd bу аn increased еxрrеѕѕiоn оf сhоlеѕtеrоl trаnѕроrtеr ABCA1. In оthеr words, саrdаrinе асtivаtеѕ the same gеnеtiс pathways that аrе invоlvеd in еxеrсiѕе. In аdditiоn, cardarine wаѕ ѕtudiеd fоr uѕе in treating саrdiо diѕеаѕе bеfоrе itѕ development wаѕ hаltеd in 2007.
How Does Cardarine work?
Endurobol stimulates glucose uptake and skeletal muscle tissue. It burns fat by stimulating the oxidation of fatty acids. It is offered as a potential treatment for obesity due to its ability to melt fat quickly. Cardarin also increased HDL by an average of 79% (good cholesterol) and decreased LDL (bad cholesterol) in ongoing phase II studies.
This makes it perfect for prim, during a steroid cycle, because it removes all the side effects of the accumulation of bad cholesterol.
Cardarine stimulates genes in the androgen receptors responsible for the use of adipose tissue as energy. In this way, the body switches to fat as the main source of energy, which contributes to their accelerated burning. The other unique feature of Cardarin is that it increases the flow of oxygen and blood circulation to muscles and tissues by 150 to 175%, this allows you to use your muscles more optimally (to do more repetitions or cardio without getting tired).
Also, increased blood circulation will help burn the hard-to-reach fats you mentioned around the abdomen, because in principle they do not get enough blood, in other words, your body will now be able to actively use them as a source of energy. If you want an even better fat-burning effect, Andarine is the best combination with Cardarin, because while caradarin stimulates the body to use fat as the main source of energy, Andarin can minimize “lipoprotein lipase” – an enzyme that causes accumulation. of fat. This automatically means that with Andarin the fat will stick to you quite hard. It also has 33% of the strength of testosterone, which means that you will be able to gain lean muscle mass.
The ability of Cardarine GW501516 to get rid of unwanted fat has become almost legendary. Like growth hormone, Endurobol generates proinflammatory markers in adipose tissue and reduces the activity of genes involved in lipogenesis. This means that your body will be able to block the formation of fatty acid chains and their storage as fat.
A study from scientific reports published in 2015 states that Endurobol acts on PPAR beta cells, causing the body to use only its own fats as a source of energy. Activation of these individual genes in the body has the potential to burn body fat at such an alarming rate that some people see Cardarin as a “solution to obesity.”
There were absolutely no side effects found during the last 20 years of the study, and muscle loss was extremely rare during the study.
Following are some of the benefits of Cardarine GW 501516:
As I already mentioned, beets with Cardarine would mainly lead to fat loss, but what exactly is the effect of this SARM supplement? Cardarine works by blocking the formation of fatty acid chains.
In essence, this means that it prevents the body from storing fat, and also uses it as a source of energy . The results are similar to the state of starvation that the body enters when food intake is scarce. However, with Cardarine, there is no deterioration in muscle mass or “muscle cannibalization”.
There is a reason why elite athletes can’t afford to miss GW 501516 in their workout regimen. There is an even bigger reason why the World Anti-Doping Agency (WADA) named GW 501516 as a banned substance. This is simply due to its potency which makes its users unbeatable.
Stamina, energy, and endurance don’t come any better than it is when using Cardarine. Your gym workouts will feel effortless, and this gives you a rare chance of intensifying your exercises even further! After intensive workouts, the biggest problem is recovery but not when you’re using Cardarine. This compound will shorten your recovery time helping you to spend more time in the gym.
The best part? All this energy and stamina is achieved without having to deal with anxiety and jittery. This is because GW 501516 doesn’t contain any stimulants and hence its impact is perfectly safe for almost all athletes.
The first thing you will feel when you take your first cycle with Cardarin GW501516 is improved cardiovascular efficiency.
Studies show that taking Cardarine significantly increases the ability to run faster in endurance tests .
Your endurance will increase like never before, which will make you increase the load more and more .
Due to its action, Cardarin drastically improves strength and endurance. This is exactly what makes WADA ( World Anti-Doping Agency ) ban this SARM supplement in all professional sports. This should give you an idea of how powerful the GW-501516 really is.
Maintains muscle mass
As long as you are calorie deficient, you may be at risk of losing muscle mass. Cardarine helps you burn fat, but it also helps you maintain muscle .
This effect is similar to what anabolic steroids do . When Cardarin begins to interact with your receptors (PPAR is activated), you not only melt fat, but also stimulate muscle fibers .
This makes it an extremely suitable assistant in the preparation periods before bodybuilding competitions.
Many athletes start using Cardarine purely for its therapeutic benefits. GW501516 helps to speed recovery from injuries and reduce inflammation in muscle tissue .
Endurobol also helps reduce inflammation in brain cells and can protect against damage caused by oxidative stress.
Lowers bad cholesterol
In one study, 13 people with abdominal fat and high cholesterol were given 2.5 mg a day of Cardarin for 6 weeks .
As a result, the levels of triglycerides, fatty acids and Apolipoprotein B (VLDL-cholesterol fall ) , which are very important indicators for the heart and heart activity . Two other studies with 305 people also showed an increase in HDL (good cholesterol) and a decrease in LDL (bad cholesterol).
Protects the liver
One of the main targets of the cycle with Cardarine GW501516 is the liver , as the liver is responsible for storing, burning and releasing fat in the body .
PPAR-delta causes the liver to change its source of energy from glucose to fatty acids , thus lowering blood sugar.
In cell studies, Cardarin has been shown to have the potential to be beneficial for liver health . Cells exposed to Endurobol produce less IL-6, which may help prevent insulin resistance. Subjects given this CAPM supplement have less liver damage as a result of a high-fructose diet and are less likely to develop non-alcoholic fatty liver.
However, cardarin causes cell death in liver cells and liver damage (fibrosis) in some mice with liver disease, which means that the use of cardarin in people with liver disease should be avoided.
If you cycle with steroids especially orally, taking Cardarin with them can also help reduce inflammation in the liver.
This SARM supplement will also prevent insulin resistance and may protect the liver from steroid-induced damage.
Protects arteries from plaque buildup
In addition to lowering cholesterol, Cardarin can have a direct effect on blood vessels. Endurobol prevents oxidative damage to blood vessels in mice. GW 501516 can reduce the risk of plaque buildup in the arteries by increasing the protective and relaxing nitric oxide for blood vessels.
Low doses of Cardarin reduce tissue damage and inflammation. A cycle with this CAPM will also help clear blood vessels, thus reducing the risk of heart disease and complications.
Endurobol cardarine increases the growth of new blood vessels in human heart cells . This can be beneficial for those with heart disease, but can be problematic if it is excessive . For example, people prone to cancer should avoid taking substances such as Cardarin, which enlarge new blood vessels.
Does not suppress hormones
Because Cardarin does not interfere with the natural production of hormones, post-cycle therapy will not be needed. GW 501516 Cardarine also has no estrogen-related side effects. This is a huge advantage over other preparations.
You can easily combine it with SARMs, and you can even take it with Stenabolic and you still won’t need therapy.
The safest fat burner
All fat burners that are commonly used by bodybuilders are known to cause heart problems that can even be fatal in the long run. Clenbuterol, for example, has been linked to atrial fibrillation and sudden heartbeat. Cardarin is probably the only product in the world that can burn fat while lowering triglyceride and LDL levels.
Cardarine and Obesity:
Obesity is a serious problem affecting so many people worldwide. Every time there is a report of a potential cure for obesity the new is, therefore, expected to spread rapidly which is exactly what has happened here.
Cardarine popularity in dealing with obesity received a major boost after a 2015 scientific report which explained how Cardarine affects PPAR beta cells. These are the cells that use body fat to produce energy during starvation. GW 501516 activates these cells and this increase the burning of body fat at insane levels without causing any negative reactions, and that’s why it was labeled the cure for obesity.
Nourishes muscle fibers
In 2015, Wei Chen investigated the effects of an increase in PPAR genes (caused by the usage of cardarine) to muscle fibers. The outcomes were astonishing. He realized that as PPAR genes increased the body’s muscle fibers were able to utilize oxygen even more and the body’s endurance also witnessed a massive boost. Increase in stamina was witnessed in lab mice that were under normal supply of oxygen and also the ones with limited oxygen. This evidently concluded that Cardarine is remarkable in boosting skeletal muscles endurance.
Another study that looked into the PPAR agonist nature of cardarine showed that while the compound enhanced endurance, it did so without affecting BCAA even when the lab mice were placed under intense exercises. This hence allowed the mice to recover at a much faster rate.
What’s even more interesting is that the lab mice in the study went ahead to witness a significant decrease in body fat and this was regardless of the diet they were on. The studies hence went further to confirm Cardarine’s ability to boost fat burning without having to change one’s lifestyle or diet!
Cardarin cycle with athletes
Given the advantages I have already described, it turns out that the Cardarine GW 501516 cycle is extremely suitable for athletes in various fields. It is no coincidence that, although a have already been declared doping, they large number of athletes continue to use it . The most recent case is with the son of our legendary wrestling coach Simeon Shterev – Nikolai, who was caught with Cardarine.
A number of athletes tested positive for GW501516. During the Vuelta Ciclista cycling race in Costa Rica in December 2012, four Costa Rican riders tested positive for Cardarine.
In April 2013, Russian cyclist Valery Kaikov was punished by the International Cycling Union UCI after being tested positive for GW 501516.
In February 2014, the Russian athlete in athletic walking Elena Lashmanova gave a positive test for GW501516.
In April 2019, heavyweight boxer Jarrell Miller tested positive for Cardarine, which caused the cancellation of the match for the world titles of Anthony Joshua in the heavyweight category.
Frequently Asked Questions about Cardarine
What is GW 501516 Cardarine?
Cardarine (Cardarine GW501516 or Endurobol) is a PPAR agonist . Endurobol is defined as a SARM supplement because of the similar way it works.
It is designed to safely treat metabolic and heart problems.
The good news is that human clinical trials have shown that taking Cardarin GW501516 activates the genes responsible for burning fat .
Additionally, Endurobol raises energy, thus actively strengthening your body so that it burns fat as an energy source.
This is very useful for people suffering from obesity. The action of Cardarin reduces the symptoms of metabolic disorders , as it increases the levels of fat burning.
Moreover, taking this CAPM supplement reduces liver fat, insulin levels and blood fats by 10 to 30%, according to some studies.
So, if you are trying to significantly improve your ability to burn fat combined with the ability to train harder for longer, you can start a cycle with Cardarine GW501516 because it will have the right effect for you.
And of course we must mention, perhaps most importantly, that all this is not at the expense of straining the heart and raising blood pressure , because Kradarin is not a stimulant.
Sounds pretty good doesn’t it? Let me introduce you to the other positive actions and effects of Cardarin GW501516.
Whаt is Cаrdаrinе Used fоr?
Cаrdаrinе iѕ grеаt fоr pretty much еvеrуthing! Inсrеdiblе еndurаnсе benefits from it аrе рrоbаblу thе most рrоminеnt rеаѕоn tо use thiѕ рrоduсt. Nоt оnlу hаѕ it рrоvеn to inсrеаѕе endurance in ѕсiеntifiс studies, but whеn you use it for уоurѕеlf you’d see thаt thе rеѕultѕ аrе nothing ѕhоrt of amazing! If уоu’rе a саrdiо junkiе оr juѕt likе gеtting lean, it inсrеаѕе уоur run timеѕ. Yоur weight lifting ѕеѕѕiоnѕ will bе еxtеndеd furthеr, you’ll fееl еnеrgizеd lоngеr and ultimаtеlу gеt a lоt mоrе work dоnе bеfоrе you wаlk оut of the gym еvеrу day.
Of соurѕе, fat lоѕѕ iѕ аt the tор of the list of rеаѕоnѕ whу many реорlе love Cardarine ѕо muсh. Striations аnd veins gеt mоrе noticeable аnd your jоurnеу tо fаt lоѕѕ bесоmеѕ a lоt easier, withоut the саtаbоliс еffесtѕ that mоѕt fаt burnеrѕ аnd drugѕ саn hаvе whilе trimming down. Fat loss frоm саrdаrinе iѕ a rеѕult of inсrеаѕеd gluсоѕе uрtаkе in skeletal muѕсlе. Essentially, you’re mаking bеttеr uѕе оf thе nutrients уоu consume every day аnd dесrеаѕing thе аmоunt оf carbohydrates оr fаt ѕtоrеd аѕ аdiроѕе tiѕѕuе. Aѕ a rеѕult, саrdаrinе iѕ nоt only fat burning аnd аnti-саtаbоliс, but it’ѕ аlѕо a little bit аnаbоliс аѕ well.
Cаrdаrinе can bе ѕtасkеd with рrеttу much аnуthing, and it will enhancess thе results оf thе сусlе. Fоr аnаbоliс-аndrоgеniс steroid uеrѕ whо likе the drug trenbolone, саrdаrinе is fantastic at соmbаting thе nеgаtivе ѕidе еffесtѕ of “trеn” аnd even enhancing thе positive еffесtѕ.
What are the benefits of Using Cardarine GW 501516?
There are so many benefits surrounding the usage of this PPAR agonist. High-quality clinical trials support these benefits, and that’s why more and more people are beginning to use Cardarine. What makes it even more ideal is that above all these benefits users rarely get any side effects.
Some of the benefits of using Cardarine include:
– Promotes the burning of fat
– Delivers results quickly. Most users of Cardarine felt its impact after just the first – dose!
– It can be used during both bulking and cutting
– Its versatile nature makes it possible for you to stack it with almost anything
– You don’t have to go through post cycle therapy
– Cardarine can run for up to 8-12 weeks
– Minimal to zero chances of side effects
– Provides an increase in energy levels up to 150% without being a stimulant
– Universal – can be combined with almost anything.
– Can be used to burn fat or gain muscle, will speed up your results in both cases
– No side effects, liver toxicity or testosterone suppression have been reported.
– There is no need for post-cycle therapy.
What are the safe / recommended doses for a Cardarine cycle?
Cardarine (Endurobol) is extremely effective at low doses of 10 to 20 mg per day. If you have no experience with GW501516, most users advise starting with a low dose.
Studies show that the effect of Cardarin GW501516 is felt with 10mg, with more remarkable benefits than fat burning, which is manifested above 20 mg per day.
The effect of Cardarine (Endurabol) lasts about 16-24 hours, which means that once daily intake is sufficient, with peak effectiveness being felt 1 to 3 hours after ingestion . For athletes who train twice, it is more optimal to take 10 mg twice a day for up to an hour before training.
The duration of the cycle can be up to 8 weeks. Even a 5-week cycle can give you great results.
Is the use of Cardarine allowed?
Cardarine as well as SARM supplements have not yet passed the full clinical trials required to be sold completely freely on the market.
While from a medical point of view the cardarin’s status is not completely clear, in terms of its status as a doping it is completely clear.
Cardarin is banned as doping for use by professional athletes, and violating this ban can bring you serious punishment.
With what to combine Cardarine?
With which SARMs supplements is it good to stack Cardarin GW501516 ?
CAPM stack with RAD 140 and / or Andarine as well as with a well-structured diet and training program will increase its effectiveness in terms of fat burning.
On the other hand, Cardarin can be combined with Andarin and / or Ostarine to easily increase lean muscle mass without accumulating fat.
Another CAPM stack with Cardarin GW501516 is its combination with Ibutamoren MK677 and Andarin S4. This stack combines high growth hormone accumulation with blocking and burning fat.
In 2 words, the result here is guaranteed, the increased metabolism and the predisposition of your body to burn the fat tissue that this SARM stack gives you guarantee visible results for a short period of time!
Where can I buy quality Cardarine in the USA at a good price?
Crazy Bulk SARMs!
Crazy Bulk is a famous brand in bodybuilding supplements industry. You can buy the highest quality SARMs including Cardarine from the Crazy Bulk Official Website.
Are there any side effects of using Cardarine?
There is not much information about side effects from Cardarin. After a long research we could not find reports from surveys or opinions of users from Bulgaria and abroad to share about the negative side effects of Cardarine.
There are no studies that confirm that Cardarine does have any side effects in humans at all, but this is still possible to change.
If you plan to experiment with Cardarin, be sure to follow the recommended dosing instructions.
Thе known side еffесtѕ оf Cardarine primarily ѕurrоund increasing thе сhаnсеѕ оf саnсеr; hоwеvеr, it’ѕ not ԛuitе thаt cut and dry. Studies thаt showed increased саnсеr rates in rats used doses of the PPAR-RA fаr аbоvе аnd bеуоnd whаt аnу human wоuld tаkе.
Furthеr, additional ѕtudiеѕ hаvе shown GW-501516 dесrеаѕеd еxiѕting саnсеrоuѕ tumоrѕ and in effect сurеd thе еxiѕting cancer. Thе truth bеhind the rеlаtiоnѕhiр with thiѕ drug аnd саnсеr iѕ unknown аt thiѕ timе. Bесаuѕе thеrе is a роtеntiаl relationship bеtwееn thе medication and саnсеr, we mау nеvеr knоw the truth as it’ѕ unlikеlу any major рhаrmасу group will undеrtаkе аnу additional ѕtudу.
Estrogenic: Thеrе аrе nо еѕtrоgеniс side effects аѕѕосiаtеd with GW-501516. Wаtеr rеtеntiоn, blоаting, gуnесоmаѕtiа and high blооd рrеѕѕurе аѕѕосiаtеd with wаtеr retention iѕ nоt роѕѕiblе as there iѕ nо conversion оf tеѕtоѕtеrоnе tо estrogen.
Androgenic: The side effects оf Cardarine dо nоt inсludе аnу оf аn androgenic nature. Hаir loss, acne аnd virilizаtiоn symptoms in wоmеn аrе not possible with thiѕ mеdiсаtiоn.
Cаrdiоvаѕсulаr: Thеrе аrе nо nеgаtivе ѕidе еffесtѕ of Cаrdаrinе аѕѕосiаtеd with саrdiоvаѕсulаr hеаlth; in fасt, liрidѕ mау imрrоvе. In a ѕtudу dоnе bу thе Journal of Cаrdiоlоgу, GW-501516 wаѕ stated to possibly rеduсе the riѕk оf heart attack.
Tеѕtоѕtеrоnе Suррrеѕѕiоn: GW-501516 will nоt suppress nаturаl tеѕtоѕtеrоnе production. Post Cусlе Therapy (PCT) iѕ nоt nееdеd whеn using thiѕ PPAR-RA.
Hepatotoxicity: Cardarine is nоt toxic tо the livеr.
Does Cardarine cause cancer?
You’ve probably heard that Cardarin can cause cancer. Although most of these claims seem to be just speculation and in fact no one provides evidence to support them.
There’s an unclear history between Cardarine and tumor and cancers which has raised concerns among users and other interested parties questioning whether or not it can influence the spread of cancer. There were allegations that if a user of Cardarine already had cancer cells that the interaction of these cells with GW 501516 will increase their growth. This raised eyebrows leading to extensive research all trying to understand the interaction between this compound and cancer cells.
Fortunately, a majority of the trials conducted showed that using Cardarine affects neither the growth nor spread of cancer cells. One study from the American Association of Cancer Research explained that PPAR agonists have zero impact on the amplification of colorectal cancer cells. The report, published in 2004, went further to explain that under normal conditions, the activation of PPAR does not influence cell growth.
The National Institute of health not only proved wrong these accusations but also confirmed that this compound could help to inhibit the development of cancer in humans!
The only detailed study conducted on mice showed that Cardarine GW501516 caused cancer.
That’s right, but what exactly is given to these mice? You can’t just take the dose of rats and compare it to a human dose.
These rats were given 0 mg, 54.9 mg, 219.6 or 439.2 mg Endurobol Per day. The lowest dose given to these rats was 55 mg per day. This is about 5 times the average dose that people use.
Let’s not forget that rats are tens or even hundreds of times smaller than a human, and compared to a person’s weight, it’s like taking one tablespoon of Cardarin protein a day.
These rats received VERY high doses. The initial study even talked about how GW-501516 (Cardarine) is able to cure cancer.
Another thing worth mentioning about this study was that rats were given Cardarin for 104 weeks (2 years) . This is an extremely long period of time, given that all data and recommendations for the use of Cardarin by humans is for periods of maximum 2 to 3 months.
In 2008, the American Association for Cancer Research showed that Cardarin could potentially reduce the development of cancer in humans.
Another study in Australia looked at men who had been taking the drug for about 6 months and had no side effects.
Further evidence that Cardarin destroys cancer cells can be found in a study of Biochem Biophys Rep. from 2016 Dec; 8: 395–402
“This study provides further evidence that GW501516-activated PPARβ / δ reduces TNFα-induced Nfkb1 activity and inflammatory signaling by directly inducing anti-inflammatory genes as well as indirectly inhibiting pro-inflammatory genes by BCL6 dissociation in human cancer cells.”
In conclusion, it can be said that taking CAPM Cardarin GW501516 in recommended doses cures cancer, but its use in extremely large doses and for an extremely long period of time may cause cancer.
Can usage of Cardarine result in liver damage?
There have been various concerns that using cardarine can damage your liver but let’s confirm to you that this is nothing but misguided speculation. The compound, in fact, makes your liver healthier and promotes healing properties. You will notice that injuries like scratches, muscle damage, and blisters take a shorter time to heal.
Concluding Cardarine Review
Cardarin GW501516 is a highly sought after product by athletes and bodybuilders around the world. Bigger muscles, improved endurance, more strength, better results.
If you are looking for a safe, clean SARM that improves performance – GW501516 is an excellent choice. The benefit-side effect ratio is almost too good to be true.
However, it is recommended to give an interval of 3 months between uses to ensure rest of the body. SARM itself has not been tested enough on humans, but Cardarin has been a favorite of sports fans for more than thirty years.
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